Algorithm to identify patients at low risk

for penicillin/beta-lactam allergy

Was the patient given a label of penicillin allergy because of:

Family history only

or

Positive skin testing, or specific IgE testing only

Yes

No

Clinical pearl:

Family history, or isolated skin testing or specific IgE testing for penicillin allergy is in not predictive of a beta-lactam allergy.